Journal: Frontiers in Immunology
Article Title: Variant-adapted COVID-19 vaccine boosters enhance humoral immunity and limit IgG4 accumulation in solid cancer patients
doi: 10.3389/fimmu.2025.1699177
Figure Lengend Snippet: Comparison of IgG4-S antibodies between oncologic patients and a control group. Oncologic patients receiving the 5 TH dose were compared with a control group at the same number of doses. IgG4-S antibodies levels are shown before (T1, panel A) and after (T2, panel B) the dose administration for the same groups. The p value of Mann-Whitney U test for unpaired data at a specific time point is reported.
Article Snippet: For IgG-N and IgM-S, the results were reported as assay index (S/C) with a positive cut-off ≥1.4 for IgG-N and ≥1 for IgM-S. IgG4-S serum levels were analyzed by standard ELISA method, using the Anti-SARS-CoV-2 antibody IgG4 Titer serologic Assay Kit (Acro Biosystem, Delaware, USA), following the manufacturer’s instructions.
Techniques: Comparison, Control, MANN-WHITNEY